Creatine Kinase MB (CK-MB) Assay Kit

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$120.00

Summary:
Creatine kinase (CK) is a dimeric enzyme occurring in four different forms: a
mitochondrial isoenzyme and the cytosolic isoenzymes CK-MM (muscle type), CKBB (brain type) and CK-MB (myocardial type). The determination of CK-MB is an important element in the diagnosis of myocardial ischemia, e.g. in acute myocardial infarction or myocarditis. CK-MB is detectable in the blood about 3-8 hours after the onset of cardiac symptoms and can be detected over a lengthy period of time. CKMB may also appear in other clinical conditions such as rhabdomyolysis and stroke.
Within the scope of laboratory diagnostics, the determination of total CK, myoglobin and troponin T can contribute to the differentiation of these clinical pictures. The sensitivity of a CK-MB determination is dependent upon the time at which the sample was taken. Follow-up assays are therefore meaningful

Category: Colorimetric Kits

Description

 

Overview
CATALOG # OttoBC137
PRODUCT NAME Creatine Kinase MB (CK-MB) Assay Kit
APPLICATIONS Fully automated analyzer, Spectrophotometer
REACTIVITY Universal
SAMPLES TYPE Serum, Plasma (Edta or Heparin)
Kit Components
Content Explanation Shelf life
Reagent-1 1x30ml 6 months
Reagent-2 1x8ml 6 months
Calibrator 1×0.5ml 6 months
Q.Control 1×0.5ml 6 months
References

1. Adams JE, Abendschein DR, Jaffe AS. Biochemical markers of myocardial injury: Is MB Creatine kinase the choice for the 1990? Circulation 1993;88:750-763.
2. Apple FS. Diagnostic markers for detection of acute myocardial infarction and reperfusion. Laboratory Medicine 1992;23:297-322.
3. Glick MR, Ryder KW, Jackson SA. Graphical Comparisons of Interferences in Clinical Chemistry lnstrumentation. Clin Chem 1986;32:470-474. Passing
4. Guder WG, Narayanan S, Wisser H, Zawta B. List of Analytes Preanalytica Variables, Broschüre in Samples: From The Patient to the Laboratory. Darmstadt: GIT Verlag 1996
5. Jockers-Wretou E, Pileider G. Clin Chim Acta 1975;58:223.
6. Neumeier D, Prellwitz W, Würzburg U et al. Determination of creatine kinase isoenzyme MB activity in serum using immunological inhibition of creatine kinase M subunit activity – Activity kinetics and diagnostic significance in myocardial infarction. Clin Chim Acta 1976;73:445-451 .
7. Remaley AT, Wilding P. Macroenzymes: Biochemical Characterization, Clinical Significance, and Laboratory Detection. Clin Chem 1989;35:2261-2270.
8. Rozenman Y, Gotsman MS. The earliest diagnosis of acute myocardial infarction. Annu Rev Med 1994;45:31-44.
9. Stein W. Med. Welt 1985;36:572
10. Szasz G Busch EW. Third European Congress of Clinical Chemistry Brighton, England 3.-8. Juni 1979 (Abstract)
11. Würzburg U et al. Klin Wschr 1976;54:357

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